Selected Presentations

Selected presentations describing Cyclocreatine Phosphate and the novel Nourin molecular biomarkers from peer-reviewed submissions to the American Heart Association (AHA), the American Association of Immunologists (AAI), Society for Cardiovascular Angiography and Interventions (SCAI), as well as an invited presentation on the anti-inflammatory drug, Cyclosporin H entitled: Cyclosporin H: A Novel Anti-Inflammatory Therapy with Applications for Covid-19 Patients.

Cyclocreatine Phosphate and Myocardial Ischemia (Review)
  • 1. Elgebaly SA, Poston R, Todd R, Helmy T, Almaghraby A, Elbayoumi T, Kreutzer DL. 2019: Cyclocreatine Protects Against Ischemic Injury and Enhances Cardiac Recovery During Early Reperfusion. Expert Review of Cardiovascular Therapy, 17:9, 683-697 (REVIEW).
  •    Preclinical Studies:
  •    - Acute Myocardial Infarction
  •    - Cardiopulmonary Bypass Surgery
  •    - Heart Transplantation
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Cyclocreatine Protects Against Ischemic Injury and Enhances Cardiac Recovery During Early Reperfusion

Cyclocreatine Phosphate and Heart Failure
  • 1. Elgebaly, S.A.; Van Buren, C.; Todd, R.; Poston, R.; Rabie, M.A.; Mohamed, A.F.; Ahmed, L.A.; El Sayed, N.S. Cyclocreatine Phosphate: A Novel Mechanism for Preventing Development of Heart Failure. Circulation. Virtual Meeting – 17 Nov 2020.142:A13311. https://www.ahajournals.org/doi/10.1161/circ.142.suppl_3.13311
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Cyclocreatine Phosphate: A Novel Mechanism for Preventing Development of Heart Failure

  • 2. Elgebaly, S.A.; Todd, R.; Kreutzer, D.; Christenson, R.; El-Khazragy, N.; Arafa, R.; Rabie, M.; Mohamed, A.; Ahmed, L.; El Sayed, N. Nourin-Associated miRNAs: Novel Inflammatory Monitoring Markers for Cyclocreatine Phosphate Therapy in Heart Failure. Int J Mol Sci. 2021 Apr; 22(7): 3575.
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Nourin-Associated miRNAs: Novel Inflammatory Monitoring Markers for Cyclocreatine Phosphate Therapy in Heart Failure

Nourin-dependent miRNA-137 Cardiac Biomarker
  • 1. Elgebaly, S.A.; Christenson, R.H.; Kandil, H.; El-Khazragy, N.; Rashed, L.; Yacoub, B.; Sharafieh, R.; Klueh, U.; Kreutzer, D.L. Abstract 13051: Nourin-dependent Mirna-137: A Novel Early Diagnostic Biomarker for Unstable Angina Patients. Circulation. Virtual Meeting – 17 Nov 2020.142:A13051. https://www.ahajournals.org/doi/10.1161/circ.142.suppl_3.13051

  • 2. Elgebaly, S.A.; Christenson, R.; Kandil, H.; El-Khazragy, N.; Rashed, L.; Yacoub, B.; Eldeeb, H.; Ali, M.; Sharafieh, R.; Klueh, U.; and Kreutzer DL. Nourin-Dependent miR-137 and miR-106b: Novel Early Inflammatory Diagnostic Biomarkers for Unstable Angina Patients. “Special Issue: Molecular Biomarkers in Cardiology”, Biomolecules . 2021 Mar; 11(3): 368.
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Nourin-dependent miR-137: A Novel Early Diagnostic Biomarker for Unstable Angina Patients

Nourin-dependent miRNA-106b Cardiac Biomarker
  • 1. Elgebaly, S.A.; Christenson, R.H.; Kandil, H.; ElKhazragy, N.; Rashed, L.; Yacoub, B.; Sharafieh, R.; Klueh, U.; Kreutzer, D.L. Abstract 13103: Nourin-dependent Mirna-106b: A Novel Early Inflammatory Diagnostic Biomarker for Cardiac Injury. Circulation. Virtual Meeting – 17 Nov 2020.142:A13103. https://www.ahajournals.org/doi/10.1161/circ.142.suppl_3.13103

  • 2. Elgebaly, S.A.; Christenson, R.; Kandil, H.; El-Khazragy, N.; Rashed, L.; Yacoub, B.; Eldeeb, H.; Ali, M.; Sharafieh, R.; Klueh, U.; and Kreutzer DL. Nourin-Dependent miR-137 and miR-106b: Novel Early Inflammatory Diagnostic Biomarkers for Unstable Angina Patients. “Special Issue: Molecular Biomarkers in Cardiology”, Biomolecules . 2021 Mar; 11(3): 368.
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Nourin-dependent miR-106b: A Novel Early Inflammatory Diagnostic Biomarker for Cardiac Injury

Nourin Protein Cardiac Biomarker
  • 1. Elgebaly SA, Christenson R, Schiffmann E, Qiao Yi. and Kreutzer DL. Early Identification of Cardiac Ischemia Patients in the Emergency Department. Catheterization & Cardiovascular Interventions. Orlando, Florida. May 2013.81:S2-S3.
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Early Identification of Cardiac Ischemia Patients in the Emergency Department

Cyclosporin H and Lethal Influenza Flu Infection (Nourin Review)
  • 1. Elgebaly SA, Elbayoumi T and Kreutzer DL. Cyclosporin H: A Novel Anti-inflammatory Therapy for Influenza Flu Patients. Journal of the Egypt. Soc. of Parasitol.: 2017 Apr;47(1):25-33.
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Cyclosporin H: A Novel Anti-Inflammatory Therapy with Applications for Covid-19 Patients

  • 2. Elgebaly SA, Daniel Perez, Kathleen Sullivan, Craig Whitaker, Stephanie Caspe, Qiao Yi, and Donald L. Kreutzer. Nourexin-4: A Novel Anti-inflammatory Therapy for Influenza Flu. J. of Immunology. Baltimore, Maryland. April 2010.184 (1 Supplement) 52.1. https://www.jimmunol.org/content/184/1_Supplement/52.1
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Nourexin-4: A Novel Anti-inflammatory Therapy for Influenza Flu

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